Amitriptyline is an antidepressant drug. Depression is an all-pervasive sense of sadness and gloom. It is believed that in some patients with depression, abnormal levels of neurotransmitters (chemicals that nerves use to communicate with each other) may relate to their depression. Amitriptyline elevates mood by raising the level of neurotransmitters in nerves of the brain. Amitriptyline was approved by the FDA in May 1983.
