Invega (Paliperidone)

Common Side Effects




 The side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.

In these studies, the most common paliperidone side effects included:

Drowsiness -- in up to 26 percent of people
Extrapyramidal symptoms (see the "Paliperidone Side Effects to Report" section that follows for more information) -- up to 23 percent
Headaches -- up to 15 percent
A rapid heart rate (tachycardia) -- up to 14 percent
Weight gain -- up to 13 percent (see Invega and Weight Gain)
Drowsiness -- up to 12 percent
Skin reactions at the injection site (for the injectable form) -- up to 10 percent
Anxiety -- up to 9 percent
Nausea -- up to 8 percent
Dizziness -- up to 6 percent
Indigestion or heartburn -- up to 6 percent
Increased saliva production -- up to 6 percent
Absent menstrual periods -- up to 6 percent.

Some other common paliperidone side effects (occurring in 2 percent to 5 percent of people) included:

Muscle tension or pain
Shakiness (tremors)
Abdominal pain (stomach pain)
Dry mouth (see Invega and Dry Mouth)
Cough
Blurred vision
Weakness
Fatigue
A fever
Constipation
Sore throat and runny or stuffy nose
Upper respiratory tract infection (such as the common cold)
Appetite changes (both increased and decreased)
Sleep problems
Cough
Back pain
Swollen tongue or tongue paralysis
General weakness
Nosebleeds
Leaky breasts
Unexplained breast enlargement.